Recombinant antigens for the detection of Coxiella burnetii

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Reexamination Certificate

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07824875

ABSTRACT:
The invention relates to a method for the detection of prior exposure toCoxiella burnetiiinfection by antibody-based assays using recombinant, immunodominantC. burnetiipolypeptides. The invention also relates to the design of biotin or His-taggedC. burnetiiproteins useful in the antibody-based assays as standardized antigen reagents.

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Murray et al. Medical Microbiology, 4th Ed. 2002 see p. 418.

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