Reagents and methods for the detection and quantification of thy

Details Reagents and methods for the detection and quantification of thy Reagents and methods for the detection and quantification of thy

1992-11-06

1994-10-25

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

562444, 562447, C07D49310

Patent

active

053590937

ABSTRACT:
Immunoassay methods and reagents for the specific quantification of thyroxine in a test sample are disclosed employing antibodies prepared with thyroxine derivatives of the formula: ##STR1## wherein P is an immunogenic carrier material and X is a linking moiety. The present invention also describes the synthesis of unique labelled reagent of the formula: ##STR2## wherein Q is a detectable moiety and W is a linking moiety, preferably fluorescein or a fluorescein derivative.

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