Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1995-05-18
1997-11-25
Ceperley, Mary E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530807, C07K 1700
Patent
active
056914563
ABSTRACT:
Immunoassay methods and reagents for the specific quantification of thyroxine in a test sample are disclosed employing antibodies prepared with thyroxine derivatives of the formula: ##STR1## wherein P is an immunogenic carrier material and X is a linking moiety. The present invention also describes the synthesis of unique labelled reagent of the formula: ##STR2## wherein Q is a detectable moiety and W is a linking moiety, preferably fluorescein or a fluorescein derivative.
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patent: 4888296 (1989-12-01), Siebert et al.
M. Bhattacharya et al., Indian Journal of Experimental Biology, vol. 26, pp. 990-992 1988.
Adamczyk Maciej
Clarisse Diana E.
Johnson Donald D.
Mattingly Phillip G.
Perkowitz Mary M.
Abbott Laboratories
Ceperley Mary E.
Pope Lawrence S.
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