Reaction product of arginine and p-aminobenzoic acid,...

Details Reaction product of arginine and p-aminobenzoic acid,... Reaction product of arginine and p-aminobenzoic acid,...

1998-02-06

2002-04-02

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

C424S078060

Reexamination Certificate

active

06365167

ABSTRACT:

BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to cosmetic and human and animal health compositions, and, more particularly, to the reaction product of arginine and p-aminobenzoic acid (PABA), and compositions thereof, useful for treating wounds, lesions, burns, sunburn, the hair and scalp, hemorrhoids and teeth, in animals and humans, including bovine mastitis.
2. Description of the Prior Art
The prior art does not disclose the reaction product of arginine and p-aminobenzoic acid (PABA), and cosmetic and health compositions and formulations thereof. For example, U.S. Pat. No. 4,499,067 discloses only acyl arginine derivatives without PABA; U.S. Pat. No. 4,921,939 discloses only forming guanidine sweetening agents by reaction of substituted arcyl amines with guanidino moieties; U.S. Pat. No. 5,110,797 discloses peptide substituted/reacted arginine, however, without PABA; and U.S. Pat. No. 5,298,647 discloses PABA/amino acid reaction products which may be used as ultraviolet protecting agents, but arginine is not disclosed.
SUMMARY OF THE INVENTION
What is described herein is the reaction product of arginine and p-aminobenzoic acid, compositions thereof, and its use in treating or preventing wounds, lesions, burns, sunburn, the hair and scalp, hemorrhoids, and teeth, in animal and humans including, bovine mastitis.
DETAILED DESCRIPTION OF THE INVENTION
The composition of the invention comprises the formulation given in Table 1 below:
TABLE 1
Composition of Invention
Percent by Wt.
Component
Suitable
Preferred
Optimum
Reaction product of
0.5-10 
1-5
2.29
arginine and p-aminobenzoic
acid (PABA) (as a powder,
aqueous solution, gel or
emulsion for example)
Biotin
  0-0.05
0.01-0.2 
0.0066
Calcium Pantothenate
0-5
0.1-0.5
0.33
Myoinositol
  0-1.0
0.1-0.5
0.33
The reaction product of arginine and PABA is prepared as follows:


REFERENCES:
patent: 5734080 (1998-03-01), Schutt

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