Rapid synthesis and screening of peptide mimetics

Details Rapid synthesis and screening of peptide mimetics Rapid synthesis and screening of peptide mimetics

1993-05-25

1995-06-06

Warden, Jill

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

530333, 525 5411, C07K 104, C07K 106

Patent

active

054224268

ABSTRACT:
A method is disclosed for the rapid synthesis of very large numbers of peptides which can be integrated with the screening of these peptides as heterogeneous mixtures to identify the specific peptides which demonstrate biological activity using a small number of coupling steps.

REFERENCES:
patent: 4631211 (1986-12-01), Houghten
patent: 4833092 (1989-05-01), Geysen
patent: 5010175 (1991-04-01), Rutter et al.
patent: 5182366 (1993-01-01), Huebner et al.
patent: 5266684 (1993-11-01), Rutter et al.
Houghten, Proc. Natl. Acad. Sci., 82, 5131-5135 (1985).
Furka, et al., Int. J. Peptide Protein Res., 37, 487-493 (1991).
Tjoeng, et al., Int. J. Peptide Protein Res., 35, 141-146 (1990).
Geysen et al., Proc. Natl. Acad. Sci., 81, 3998-40002 (1984).
Scott et al., Science, 249, 386-249 (1990).
Furka et al., (1988, 14th Int'l Congress of Biochemistry vol. 5, Abstract FR:013).
Furka et al., Xth International Symposium on Medicinal Chemistry, Abstracts, Budapest, Hungary, Aug. 15-19, 1988.
Furka et al., "More Peptides By Less Labour", Poster Presentation at Xth International Symposium on Medical Chemistry, Budapest, Hungary, Aug. 15-19, 1988.
Furka et al., "Cornucopia of Peptides by Synthesis", Poster Presentation at 14th International Congress of Biochemistry, Prague, Czechoslovakia, Jul. 10-15, 1988.

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