Rapid detection of antibiotic resistance in mycobacterium tuberc

Details Rapid detection of antibiotic resistance in mycobacterium tuberc Rapid detection of antibiotic resistance in mycobacterium tuberc

1998-05-20

2000-09-26

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 732, 435 911, 435 912, 536 231, 536 232, C12Q 168, C12P 1934, G01N 33509, C07H 2104

Patent

active

061240982

ABSTRACT:
A nucleotide sequence encoding a katG/lacZ fusion protein is useful for assaying the enzymatic activity of the katG gene product. A process of selecting a compound that is toxic against an isoniazid-resistant mycobaterial strain comprises incubating a catalase peroxidase enzyme with an isoniazid to produce a compound that restores isoniazid susceptability to the isoniazid-resistant mycobaterial strain.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 5633131 (1997-05-01), Heym et al.
patent: 5871912 (1999-02-01), Heym et al.
Heym et al. (1992), Research in Microbiology, vol. 143, No. 7, pp. 721-730.
Jin et al. (1988), Journal of Molecular Biology, vol. 202, No. 1, pp. 45-58.
Sriprakash et al. (1970), The Journal of General Microbiology, vol. 60, No. 1, pp. 125-132.
Telenti et al. (1993), The Lancet, vol. 341, No. 8846, pp. 647-650.
Zhang et al. (1992), Nature, vol. 358, No. 6387, pp. 591-593.
Prescott et al Microbiology pp. 253-256, 1990.
CDC MMWP vol. 39 No. 22 pp. 369-372, 1990.
Devi et al Biochem J. vol. 149 pp. 187-197, 1975.

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