Rapamycin esters

Details Rapamycin esters Rapamycin esters

1993-06-08

1995-01-03

Chang, Celia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540455, C07D45706, A61K 3133

Patent

active

053786963

ABSTRACT:
A compound of the structure ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are each, independently, hydrogen or ##STR2## with the proviso that R.sup.1, R.sup.2, and R.sup.3 are not all hydrogen; R.sup.4 is --(CH.sub.2).sub.m X(CH.sub.2).sub.n CO.sub.2 R.sup.5 or ##STR3## R.sup.5 and R.sup.6 are each, independently, hydrogen, alkyl, alkenyl, alkynyl, (CH.sub.2).sub.p NR.sup.9 R.sup.10, mono-, di-, or tri-hydroxyalkyl, aralkyl, or aryl; ##STR4## R.sup.7, R.sup.8, R.sup.9, and R.sup.10 are each, independently, hydrogen or alkyl;

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