Radiopharmaceuticals for diagnosing Alzheimer's disease

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – X-ray contrast imaging agent

Reexamination Certificate

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C424S001110, C424S001810, C424S001850, C424S009100, C424S001890

Reexamination Certificate

active

06872381

ABSTRACT:
This invention is directed to the use of radiopharmaceuticals in diagnosing Alzheimer's disease. In particular the radiopharmaceuticals of the invention are able to pass through the blood-brain barrier and bind to the CCR1 receptor present in brain tissue of patients having Alzheimer's disease.

REFERENCES:
patent: 5286728 (1994-02-01), Ferrini
patent: 5358712 (1994-10-01), Efange et al.
patent: 5721243 (1998-02-01), Efange et al.
patent: 5919797 (1999-07-01), Goodman et al.
patent: 6207665 (2001-03-01), Bauman et al.
patent: 6676926 (2004-01-01), Hilger et al.
patent: 2 758 328 (1998-07-01), None
patent: WO 9216239 (1992-10-01), None
patent: WO 9601656 (1996-01-01), None
patent: WO 9802151 (1998-01-01), None
patent: WO 9951594 (1999-10-01), None
patent: WO 0014086 (2000-03-01), None
patent: WO 0042011 (2000-07-01), None
patent: WO 0058305 (2000-10-01), None
K. Bergström et al., “Iodine-123 labelled Z-(R,R)-IQNP: a potential radioligand for visualization of M1and M2muscarinic acetylcholine receptors in Alzheimer's disease”, European Journal of Nuclear Medicine, vol. 26, No. 11, pp. 1482-1485, Nov. 1999, XP-002193046.
S. Oya et al., “Small and neutral TcvO.BAT, bisaminoethanethiol (N2S2) complexes for developing new brain imaging agents”, Nuclear Medicine & Biology, vol. 25, pp. 35-140, 1998.
A. Fischman et al., “Rapid detection of parkinson's disease by SPECT with altropane: A selective ligand for dopamine transporters”, SYNAPSE, vol. 29, pp. 128-141, 1998.
J. Logan et al., “Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects”, Journal of Cerebral Blood Flow and metabolism, vol. 10, pp. 740-747, 1990.
J. Seibyl et al., “Iodine-123-β-CIT an diodine-123-FPCIT SPECT measurement of dopamine transporter in healthy subjects and parkinson's patients”, The Journal of Nuclear Medicine, vol. 39, No. 9, pp. 1500-1508, Sep. 1998.
M. Melloul et al., “Double-Phase99mTc-sestamibi scintimammography and trans-scan in diagnosing breast cancer”, The Journal Of Nuclear Medicine, vol. 40, No. 3, pp. 380, Mar. 1999.
J.L. Moretti et al., “Comparison of brain SPECT using99mTc-Bicisate (L,L-ECD) and [123I]IMP in cortical and subcortical strokes”, Journal Of Cerebral Blood Flow And Metabolism, vol. 14 (Suppl. 1), pp. S84-S90, 1994.
J.M. Links, “Visual Interpretation,” Chapter 22 in HN Wagner et al. (Eds.), Principles of Nuclear Medicine, W.B. Saunders Company, 2ndEdition, 1995, pp. 391-392.
EL Palmer et al. (Eds.), Practical Nuclear Medicine, Chapter 3 “Cardiovascular Imaging,” W.B. Saunders Company, 1992, pp. 71-120.

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