Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1998-11-06
2000-09-19
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
A61K 31135
Patent
active
061213284
ABSTRACT:
Pharmaceutical formulations of mixtures of the D and L configuration of propranolol are disclosed which have antioxidant activity and reduced .beta. blocking activity.
REFERENCES:
Freedman et al., Free Radical Biology & Medicine, 11(2), 197-206, 1991.
Messerli, Franz H., Cardiovascular Drug Therapy, WB Saunders Company, 1990; Part II, Chapter 32, "Noncardioselective .beta.-Adrenoreceptor Blockers," Nies, Alan S., pp. 420-441.
Weglicki, W.B. et al., Mechanisms of Cardiovascular Drugs as Antioxidants, J Mol Cell Cardiol 22, pp. 1199-1208 (1990).
Drehkoff W. Dennis
Spivack Phyllis G.
The George Washington University
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