Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
2006-12-08
2010-06-01
Puttlitz, Karl J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C544S105000, C544S238000, C544S333000, C546S152000, C546S157000
Reexamination Certificate
active
07728130
ABSTRACT:
This invention relates to new quinolone based compounds that exhibit prolyl hydroxylase inhibitory activity. This invention also relates to methods of increasing HIF levels or activity in a subject or treating a condition associated with HIF levels or activity in a subject by administering to the subject at least one quinolone based compound. This invention further involves assays for the detection of a hydroxyproline residue in a HIF molecule.
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Allen Jennifer R.
Biswas Kaustav
Burli Roland
Dao Jennifer
Frohn Michael J.
Amgen Inc.
Jones Day
Nwaonicha Chukwuma O
Puttlitz Karl J
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