Quinolin-2-yl-methoxybenzylhydroxyureas

Details Quinolin-2-yl-methoxybenzylhydroxyureas Quinolin-2-yl-methoxybenzylhydroxyureas

1993-02-17

1995-03-21

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546153, 546155, 546159, 546171, C07D21506, C07D21512, C07D21514, C07D21516

Patent

active

053996984

ABSTRACT:
The novel quinolin-2-yl-methoxybenzylhydroxyureas can be prepared by reaction of appropriate ketones with hydroxylamine and reduction of the ketoximes and subsequent reaction with isocyanates. The new substances can be employed as active substances in medicaments.

REFERENCES:
Chemical Abstracts 115:158986 of WO 9106538, 1991.
Chemical Abstracts 115:256016 of EP 399818, 1990.
C. King, J. Org. Chem., 1960, pp. 352-356.
Gunther E. Jeromin, Chem. Ber., 1987, pp. 649-651.
Pierre Borgeat, Proc. Nat. Acad. Sci USA, May 1979, pp. 2148-2152.
Houben-Weyl VIII, 1952, p. 128, Methoden Der Organischen Chemie.
Franz Effenberger, Chem. Ber., 1964, pp. 1576-1583.
Dr. H. Ulrich, Angewandte Chemie, Aug. 21, 1966, pp. 761-788.
Chemical Abstracts 85(25):192382a, 1976.
Houben-Weyl, vol. XI/1, 1957, Methoden Der Organischen Chemie, table of contents page.
Houben-Weyl, vol. XI/2, 1958, Methoden Der Organischen Chemie, table of contents page.
Dr. H. Ulrich, (English translation of Angewandte Chem. Internat. Edit./vol. 5 (1966) No. 8 pp. 704-711). "Synthesis of Isocyanates and Carbodiimides".

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