Pyrrolidinone glucokinase activators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S343000, C514S361000, C514S367000, C514S371000, C514S375000, C514S376000, C514S407000, C544S405000, C546S278700, C548S128000, C548S163000, C548S195000, C548S217000, C548S229000, C548S361100, C548S364100, C548S364400, C548S365700

Reexamination Certificate

active

07741327

ABSTRACT:
Provided herein are compounds of the formula (I):as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.

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M.C.T. Fyfe, Diabetologia, DOI 10.1007/s00125-007-0646-8.

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