Pyronin antibacterials, process and novel intermediates thereto

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549292, 549356, 560211, 568449, 568840, 5689095, C07C 3303, C07C 4526, C07C 6730, C07D30932

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active

060229837

ABSTRACT:
The present invention provides convergent processes for preparing myxopyronins and corallopyronins, compounds useful as antibacterial therapeutics. The present invention also provides novel compositions of matter which are useful for the preparation of pyronin antibiotics.

REFERENCES:
Kohl et al., Die Biosynthase des Antibiotikume Myxopyronin A aus Myxococcus fulvus Stamm Mx f50, Liebigs Ann. Chem. 1984 1088-1093.
Jansen et al., Chemical Abstract, 103:3291, 1985.
Jarolim et al., Chemical Abstract, 85:123296, 1976.
Kohl et al., Chemical Abstract, 101:87146, 1984.
Sharma et al., Chemical Abstract, 99:38646, 1982.

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