Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-11-29
1988-08-09
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514557, 514560, A61K 3119, A61K 3120, A61K 3140
Patent
active
047628510
ABSTRACT:
The invention relates to pyroglutamic acid esters used as dermal penetration enhancers for therapeutic agents having poor skin permeation.
REFERENCES:
patent: 4540572 (1985-09-01), Seth
patent: 4555524 (1985-11-01), Gruber et al.
patent: 4670524 (1987-06-01), Kamishita
Chem. Abst., 104 (1986)--116111g, refers to Japanese Pat., Oct. 28, 1985.
Alexander Jose
Higuchi Takeru
Friedman Stanley J.
Merck & Co. , Inc.
Polk Manfred
Sudol Michael C.
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