Pyrimidinone compounds as calcilytics

Details Pyrimidinone compounds as calcilytics Pyrimidinone compounds as calcilytics

2004-04-07

2009-02-17

Berch, Mark L (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S269000, C514S258100, C514S266310, C544S284000, C544S289000, C544S298000, C544S253000

Reexamination Certificate

active

07491728

ABSTRACT:
The pyrimidinone compounds are disclosed. Methods of preparing the pyrimidinone compounds are also disclosed.

REFERENCES:
patent: 3185689 (1965-05-01), Ruschg et al.
patent: 5300477 (1994-04-01), Tice
patent: 5726124 (1998-03-01), Tice et al.
patent: 5948775 (1999-09-01), Koko et al.
patent: WO 2004/092121 (2004-10-01), None
Nemeth, J. Molec. Endocrin., 2002, 29, 15-21.
Fox, Current Opinion in Pharm, 2002, 2: 338-344.
Nemeth, Cell Calcium, 35 (2004) 283-289.
Stewart, N. Eng. J. Med. 351: 4, Jul. 2004, 324-326.
Cunningham, J. Am. Soc. Nephrol. 18: 223-234, 2007.
Stajer, et al., Magyar Kemiai Folyoirat (1986), 92(5), 234-6 (Abstract).
Fulop, et al., Synthesis (1985), (12), 1148-9.
Schubert, et al., Journal fuer Praktische Chemie (Leipzig) (1970), 312(3), 494-506.
Sprio, et al., Ann. di Chim. (Rome, IT) (1970), 60(5), 393-6.
Kato, et al., Yakugaku Zasshi (1970), 90(4), 509-11.
Mitter, et al., Quart. J. Indian Chem. Soc. (1927), 4, 149-57.
Mitter, et al., Quart. J. Indian Chem. Soc. (1925), 2, 61-70.
Mitter, et al., Journal of the Chemical Society, Transactions (1923), 123, 2179-84.
Arai, et al., Heterocycles (2001), 55(12), 2283-2287.
Tice, et al., Tetrahedron (2001), 57(14), 2689-2700.
Jayakumar, et al., Tetrahedron Letters (2001), 42(11), 2235-2237.
Rossi, et al., Tetrahedron (1999), 55(22), 6921-6970.
Mukherjee, et al., Heterocycles (1998), 47(2), 933-950.
Rossi, et al., Tetrahedron (1997), 53(41), 14107-14114.
Holzer, et al., Liebigs Annalen der Chemie (1994), (9), 901-9.
Mazumdar, et al., Tetrahedron (1994), 50(25), 7579-88.
Gupta, et al., India Patent 158084, issued Aug. 30, 1986.
Jeong, An Efficient Synthesis of 3-Substituted 3H-Pyrimidin-4ones, Organic Letters, vol. 6, No. 6, 2004 (pp. 1013-1016).
Juby, Peter F., et al: “Antiallergy agents. 2. 2-Phenyl-5-(1H-tetrazol-5-yl) pyrimidin-4(3H)-ones” Journal of Medicinal Chemistry (1982) 25(10), 1145-50.
Database Caplus [Online], Chemical Abstracts Service, Columbus, Ohio, US; Krivopalov, V.P. et al: ynthesis of 2- and 4-chloroprimides bearing hydroxyphenyl substituents by reaction of Vilsmeier-Haack reagents with (hydroxyphenyl)pyrimidin-2- and -4-ones XP002484028 1993.
Database Caplus [Online], Chemical Abstracts Service, Columbus Ohio, US; Krivopalov, V.P., et al: “Method of preparing chloro azines containing an o-hydroxyphenyl group” XP002484029 1995.
Database Caplus [Online] Chemical Abstracts Service, Columbus, Ohio, US; Miyazaki, Hiroshi, et al: “2-Substituted-4-methyl-6-pyrimidone” XP002484027 1973.

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