Pyrimidine derivatives and guanine derivatives, and their use in

Details Pyrimidine derivatives and guanine derivatives, and their use in Pyrimidine derivatives and guanine derivatives, and their use in

1998-06-02

2000-08-01

Wilson, James O.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 46, 514 47, 514 48, 536 2713, 536 272, 536 2721, 536 277, 536 278, 536 2781, 536 284, 536 2854, A01N 4304, C07H 1900

Patent

active

060967242

ABSTRACT:
The present invention provides certain 6-hetarylalkyloxy pyrimidine derivatives of formula II ##STR1## wherein R is (i) a cyclic group having at least one 5- or 6-membered heterocyclic ring, optionally with a carbocyclic or heterocyclic ring fused thereto, the or each heterocyclic ring having at least one hetero atom chosen from O, N, or S, or a substituted derivative thereof; or (ii) phenyl or a substituted derivative thereof,

REFERENCES:
patent: 5091430 (1992-02-01), Moschel et al.
patent: 5260291 (1993-11-01), Lunt et al.
patent: 5352669 (1994-10-01), Moschel et al.
Chemical Abstracts, vol. 101, No. 25, Dec. 17, 1984, Columbus, Ohio, US; Abstract No. 230466q, p. 765; column R; XP00208572, see abstract & Heterocycles, vol. 22, No. 8, 1984, pp. 1789-1790, Ram SIYA, et al.
The Journal of Organic Chemistry, vol. 34, No. 7, Jul. 1969, pp. 2160-2163, XP002028568 Morris J. Robins et al., p. 2161, column 2, formula 13.
Journal of Medicinal Chemistry, vol. 38, No. 2, Jan. 20, 1995, pp. 359-365, XP002028569 Mi-Young Chae, et al.
Journal of Medicinal Chemistry, vol. 37, No. 3, Feb. 4, 1994, pp. 342-347, XP002028570 Mi-Young Chae, et al.
Journal of Medicinal Chemistry, vol. 35, No. 23, Nov. 13, 1992, pp. 4486-4491, XP002028571, Robert C. Moschel, et al.
Cancer Research, vol. 46, Sep. 1986, pp. 4500-4504. M. Eileen Dolan, et al.
Cancer Chemotherapy & Pharmacology, 1989, vol. 25, pp. 103-108, M. Eileen Dolan, et al.
Biochemistry, 1993, vol. 32, pp. 11998-12006, A. E. Pegg, et al.
Anti-Cancer Drug Design, 1994, vol. 9, pp. 401-408, C.E. Arris, et al.
Biochemical Pharmacology, 1994, vol. 48, pp. 2127-2134, U.K. Marathi, et al.
Proc. Natl. Acad. Sci. USA, 1990, vol. 87, pp. 5368-5372, M. Eileen Dolan et al.
Cancer Communications, 1990, vol. 2, No. 11, pp. 371-377, M. Eileen Dolan, et al.
Cancer Research, 1994, vol. 54, pp. 5123-5130.
Journal of Medicinal Chemistry, 1977, vol. 20, No. 3, pp. 341-344, Abelardo P. Martinez, et al.
Journal of Medicinal Chemistry, 1975, vol. 18, No. 10, pp. 968-973, Brajeswar Paul, et al.
Tetrahedron Letters, 1985, vol. 26, No. 15, pp. 1815-1818, Malcolm MacCross, et al.
Anti-Cancer Drug Design, 1995, vol. 10, pp. 75-95, J.E.A. Wibley, et al.
Biochemical Pharmacology, 1995, vol. 50, pp. 1141-1148, A.E. Pegg, et al.
Cancer Research, 1995, vol. 55, pp. 4606-4610, S.L. Berg, et al.
Cancer Research, 1995, vol. 55, pp. 2853-2857, M. Eileen Dolan, et al.

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