Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-03-03
1977-03-22
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
42424854, 2602472A, 2602564N, C07D23926
Patent
active
040137686
ABSTRACT:
Compounds of the formula ##STR1## in which R is aminocarbonylphenyl in which amino is --NH.sub.2, pyrrolidino, piperidino or morpholino, and Ar is phenyl substituted with chloro, fluoro, trifluoromethyl, methylenedioxy or one or more methoxy.
The compounds are prepared by 2-Ar-4-chloro-pyrimidin-6-yl ethylacetate with ##STR2## and then reacting that reaction product with hydroxylamine hydrochloride. The compounds possess vasodilatatory, anti-ulcerous, respiratory analeptic, hypotensive, diuretic, anti-depressive, analgesic, anti-inflammatory and neurotropic properties.
REFERENCES:
patent: 3876636 (1975-04-01), Fauran et al.
Fauran et al., "Chem. Abstracts", vol. 82, (1975), No. 171,040k.
Fauran et al., "Chem. Abstracts", vol. 79, (1973), No. 32093e.
Bourgery Guy R.
Eberle Jeannine A.
Fauran Claude P.
Gouret Claude J.
Raynaud Guy M.
Delalande S.A.
Jiles Henry R.
Ramsuer R. W.
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