Pyridyloxymethyl and benzisoxazole azabicyclic derivatives

Details Pyridyloxymethyl and benzisoxazole azabicyclic derivatives Pyridyloxymethyl and benzisoxazole azabicyclic derivatives

2004-03-12

2008-03-18

Tucker, Zachary C (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S249000, C544S349000, C540S599000

Reexamination Certificate

active

07345038

ABSTRACT:
An aminomethylpyridyloxymethyl/benzisoxazole substituted azabicyclic compound of formula I, pharmaceutical composition comprising same, and a method of treating one or more CNS or other disorders, including concurrent treatment of disorders such as schizophrenia and depression, wherein formula I isor a pharmaceutically acceptable salt or thereof, wherein Z iswherein Y is methylene; X is oxygen; n is 0; R1and R2are each hydrogen or halogen; and R3and R4together with the nitrogen atom to which they are attached form i) a saturated non-aromatic 3 to 7 membered monocyclic ring, said ring i) being unsubstituted or substituted or substituted with one or more (C1–C4)alkyl, (C1–C4)alkoxy(C1–C4)alkyl, or hydroxy groups.

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