Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1987-05-07
1988-05-31
Schwartz, Richard A.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544238, 544284, 544316, 544333, 544353, 544354, 544355, 544356, 544405, 546 82, C07D47104
Patent
active
047482460
ABSTRACT:
There are disclosed compounds of the formula ##STR1## wherein the various substituents are defined hereinbelow, and, by virtue of their ability to inhibit interleukin 1, their use as antiinflammatory agents and in treatment of disease states involving enzymatic tissue destruction.
REFERENCES:
Sangwan, N., et al., Indian Journal of Chemistry, 24B, 639-644 (1985).
Chemical Abstracts, 88:99030m (1978), [NASR, M. et al., J. Med. Chem. 1978, 21, (3), 295-8].
Gilman Steven C.
Musser John H.
Skotnicki Jerauld S.
Steinbaugh Bruce A.
American Home Products Corporation
Schwartz Richard A.
Tarnowski George
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