Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-09-18
2007-09-18
Morris, Patricia L. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S406000, C548S370100, C548S371700, C548S375100
Reexamination Certificate
active
10549226
ABSTRACT:
The compounds of formula I:inhibit gamma secretase and hence are of utility in the treatment or prevention of Alzheimer's Disease.
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Holsher, “Development of beta-amyloid, etc.,” Reviews in the Neurosciences (2005), 16(3), 181-212.
Behr et al., “Protease Inhibitors, etc.,” Expert Opin. Investig. Drugs (2005), 14(11), 1385-1409.
Dewachter et al., “Secretases as targets, etc.,” The Lancet Neurology, 1, 2002, 409-416.
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Bettati Michela
Chambers Mark Stuart
Hunt Peter Alan
Jones Philip
MacLeod Angus Murray
Krovatin William
Merck Sharp & Dohme Ltd.
Morris Patricia L.
Todaro John C.
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