Purification of taxanes and taxane mixtures using...

Details Purification of taxanes and taxane mixtures using... Purification of taxanes and taxane mixtures using...

2011-03-01

2011-03-01

Andres, Janet L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S511000

Reexamination Certificate

active

07897796

ABSTRACT:
This invention is directed to a method for isolating and/or purifying one or more taxanes from materials comprising taxanes. In one embodiment, the method comprises the steps of: (a) treating a taxane containing material with an amino containing material attached to a solid matrix, such as a polyethyleneimine-bonded silica chromatographic resin; (b) eluting the desired taxane compound from the resin; and (c) recovering the eluted taxane compound.

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Wu et al., “Preparative Separation of Taxol in Normal- and Reversed-Phase Operations,”Journal of Chromatography, 1995, pp. 233-241.

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