Purification of C-076 compounds by single column chromatography

Details Purification of C-076 compounds by single column chromatography Purification of C-076 compounds by single column chromatography

1977-10-03

1979-10-30

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 1708

Patent

active

041729404

ABSTRACT:
This case relates to a novel process for aiding in the isolation and purification of novel compounds which are produced by the microorganism, Streptomyces avermitilis. The process described herein utilizes a bed of activated alumina and a bed of activated carbon, respectively. The compounds which are isolated and purified are described generically as C-076 and have significant parasiticidal activity.

REFERENCES:
patent: 3950360 (1976-04-01), Aoki et al.
Mishima et al. Tetrahedrun Letters 10, pp. 711-714, 1975.
Jour. of Antibiotics 29(6), Jun. 1976, pp. 76-35 to 76-42 and pp. 76-14 to 76-16.
Derwent Abstracts 76268w/46 to Sankyo Co.
Snyder et al. Introduction to Modern Liquid Chromatography, John Wiley & Sons.

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