Pseudorabies diagnosis probes

Details Pseudorabies diagnosis probes Pseudorabies diagnosis probes

1990-06-13

1993-06-01

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, 435 91, 536 2432, C12Q 170, C12Q 168, C12P 1934, C07H 2100

Patent

active

052158810

ABSTRACT:
Regions in the pseudorabies virus genome in the unique long region and the internal repeat sequence contain nucleotide sequences which are unique to latent infection of the virus. These regions are the basis for constructing nucleic acid probes and antigens useful in distinguishing latent pseudorabies infection from productive infection.

REFERENCES:
patent: 4711850 (1987-12-01), Kit et al.
Jordan Spivak et al. Journal of Virology, vol. 65(12) pp. 6800-6810, Dec. 1991.
Wagner et al. (Dec. 1988) "The Herpes Simplex Virus Latency Associated Transcript is spliced during latent phase infection; Journal of Virology", vol. 62(12) 4577-4585.
H.-J. Rziha et al., "Studies on Reactivation of Latent Pseudorabies Virus from Lymphoid Blood Cells," Abstract, 14th International Herpesvirus Workshop, Denmark (1989).
Andrew K. Cheung, "Cloning of the Latency Gene and the Early Protein O Gene of Pseudorabies Virus," J. Virol. 65(10): 5260-5271 (Oct. 1991).
Gutekunst, D. E. (1979)"Latent Pseudorabies Virus Infection in Swine Detected by RNA-DNA Hybridization" American Journal of Veterinary Research 40(11), pp. 1568-1572.
Falser, N. et al. (1986) Journal of Virology, vol. 57(1), pp. 335-339.
Wagner, E. K. et al. (1988) Journal of Virology, vol. 62(4), pp. 1194-1202.
Rziha, H.-J. et al. (1986) Virology, vol. 155, pp. 600-613.
Andrew K. Cheung, "Fine Mapping of the Immediate-Early Gene of the Indiana-Funkhauser Strain of Pseudorabies Virus," J. Virol. 62(12):4763-4766 (Dec. 1988) (I).
Andrew K. Cheung, "Detection of Pseudorabies Virus Transcripts in Trigeminal Ganglia of Latently Infected Swine," J. Virol. 63(7):2908-2913 (Jul. 1989) (II).
Andrew K. Cheung, "DNA Nucleotide Sequence Analysis of the Immediate-Early Gene of Pseudorabies Virus," Nucl. Acid Res. 17(12): 4637-4646 (1989) (III).
Andrew K. Cheung, "The BamHI J Fragment (0.706 to 0.737 Map Units) of Pseudorabies Virus is Transcriptionally Active During Viral Replication," J. Virol. 64(3): 977-983 (Mar. 1990) (IV).

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