Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Plant proteins – e.g. – derived from legumes – algae or...
Patent
1994-06-06
1997-05-20
Ketter, James S.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Plant proteins, e.g., derived from legumes, algae or...
536 236, C07K 14415, C12N 1529
Patent
active
056313489
ABSTRACT:
This invention relates to substantially purified gelonin, toxic fragments thereof, the DNA sequences encoding gelonin and use of the DNA for producing, by recombinant technology, gelonin, toxic fragments thereof and fusion proteins. More specifically, the invention relates to the primary amino acid sequence of gelonin, and of the DNA encoding said gelonin and the production of synthetic gelonin and toxic fragments thereof.
REFERENCES:
patent: 4446240 (1984-05-01), Nerenberg
patent: 4810648 (1989-03-01), Stalker
patent: 4888415 (1989-12-01), Lambert et al.
patent: 4921802 (1990-05-01), Hall et al.
Lambert et al., Cancer Treat. Res., vol. 37, 1988, pp. 175-209.
Ronneberger, Dev. Biol. Stand., vol. 71, 1990, pp. 185-190.
Benoit et al., Curr. Eye Res., vol. 9 Suppl., 1990, pp. 201-205.
Roselli et al., J. Nuclear Med., vol. 30, 1989, pp. 672-682.
Dunbar, Two-Dimensional Electrophoresis and Immunological Techniques, 1987, Plenum Press, New York, pp. 32-34.
Stirpe et al., J. Biol. Chem. v. 255, 1980, pp. 6947-6953.
Jacobs, et al., Nature v. 313, 1985, pp. 806-810.
Falasca et al., Biochem. J. v. 207, 1982, pp. 505-509.
Sivam et al., Cancer Res. v. 47, 1987, pp. 3169-3173.
Young et al., Science v. 222, 1983, pp. 778-782.
Toy, J. L., Clin. Exp. Immunol., 1983, 54, 1-13.
Aggarwal Bharat
Kohr William J.
Rosenblum Michael
Adler Benjamin Aaron
Ketter James S.
The Research Development Foundation
LandOfFree
Protein sequence of the plant toxin gelonin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Protein sequence of the plant toxin gelonin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein sequence of the plant toxin gelonin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1724737