Protein protease inhibitors from streptomyces

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 9152, 4351723, 4352523, 435 9153, 536 237, 530350, 935 11, C12Q 168, C12N 1500, C12N 1531, C12N 1510, C12N 1511, C07K 1504, C07K 1300

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active

052799395

ABSTRACT:
This invention relates to novel protein protease inhibitors as well as DNAs encoding same and vectors and transformed host cells useful for the recombinant production of the inhibitors.

REFERENCES:
patent: 4014860 (1977-03-01), Kahinuma et al.
patent: 4506013 (1985-03-01), Hershberger et al.
Verweij et al.; Nucleic Acids, Res. 13: 4699 (1985).
Young et al.; Proc. Natl. Acad. Sci. USA 80: 1194 (1983).
Sugino et al.; J. Biol. Chem. 253: 1546 (1978).
Ikenaka et al.; J. Biochem. 76: 1191 (1974).
Bezborodov et al.; Chem. Abstr. 102: 217993k (1985).
Helfman et al.; Proc. Natl. Acad. Sci. USA 80: 31 (1983).
Goeddel et al.; Nature 281: 544 (1979).
Hiromi et al., Elsevier pp. 1-14, 139-161, and 363-395 (1985).
Brawner et al. Gene 40: 191-201 (1985).

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