Protein kinase C assay

Details Protein kinase C assay Protein kinase C assay

1996-11-19

1998-07-07

LeGuyader, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

4351723, 435194, 43525421, 4353201, 536 281, C12Q 168, C12N 1500, C12N 912, C07H 2102

Patent

active

057766851

ABSTRACT:
A method evaluating the tumor promoter agonist or antagonist activity or the PKC activator or inhibitor activity of a compound. The method includes supplying a yeast cell expressing a PKC , contacting the yeast cell with a compound to be evaluated; and determining the value of a parameter related to tumor promoter agonist or antagonist or PKC activator or inhibitor activity in the cell, the effect of compound on the value of the parameter being indicative of the tumor promtoer or PKC activator or inhibitor activity of the compound.

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