Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-04-25
2006-04-25
Bugaisky, Gabriele (Department: 1653)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S320100, C435S254230, C435S254110, C435S252300, C514S012200, C530S300000, C530S324000, C536S023500
Reexamination Certificate
active
07033788
ABSTRACT:
The present invention relates to Saxatilin, a protein derived from the venom of a Korean snake,Agkistrodon saxatilis emelianov, a process for preparing Saxatilin, and pharmaceutical application of the same as anti-platelet aggregation agent and anti-tumor agent. The present inventors purified Saxatilin from the venom ofAgkistrodon saxatilis emelianov, cloned its cDNA, and prepared recombinant Saxatilin by culturing a microorganism transformed with an expression vector containing the cDNA. Saxatilin effectively suppresses the platelet aggregation and angiogenesis of tumor cells, which makes possible its practical application as an active ingredient of anti-platelet agent and anti-tumor agent.
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Chung Kwang-Hoe
Hong Sung-Yu
Huh Chin-Kyu
Jang Yang-Soo
Kim Doo-sik
Bugaisky Gabriele
Chung Kwang-Hoe
Darby & Darby
Kim Doo-sik
LandOfFree
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