Protein delivery system using human papillomavirus...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C424S186100, C424S192100, C424S204100, C435S455000, C435S456000, C435S320100, C435S325000, C435S366000, C435S371000, C536S023100, C536S023720, C514S002600

Reexamination Certificate

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06991795

ABSTRACT:
Human Papillomavirus virus like particles (VLPs) have been constructed so that they contain a modified L2 protein. The L2 protein has been minimized and is fused to a second protein or peptide. The fused protein is incorporated into the VLP and the VLP can deliver the protein to a cell. The modified VLPs can be used to increase the breadth of immune response in vaccine preparations or to deliver other proteins of interest.

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