Programmable molecular manipulating devices

Radiant energy – Inspection of solids or liquids by charged particles

Reexamination Certificate

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C435S006120

Reexamination Certificate

active

10965173

ABSTRACT:
A system manipulates molecules using a set of proximal probes such as those used in atomic force microscopes. An electrostatic pattern is placed on a set of proximal probes such that each proximal probe may exert an electrostatic force. A molecule is captured using those electrostatic forces, after which the molecule can be manipulated while the molecule remains captured by the proximal probes. The electrostatic pattern can be modified such that the molecule moves and/or rotates over the set of proximal probes while the molecule remains captured by the set of proximal probes. The electrostatic pattern can be used to bend or split the molecule while the molecule remains captured by the set of proximal probes, thereby allowing the system to engage the molecule in chemical reactions, e.g., to act as a synthetic catalyst or a synthetic enzyme.

REFERENCES:
patent: 5730940 (1998-03-01), Nakagawa
patent: 5744799 (1998-04-01), Ohara
patent: 6287765 (2001-09-01), Cubicciotti
patent: 6312960 (2001-11-01), Balch et al.
patent: 6475730 (2002-11-01), Douglas et al.
patent: 6727065 (2004-04-01), Weiss et al.
patent: 6803238 (2004-10-01), Eggers

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