Process for the production of cephalosporins

Details Process for the production of cephalosporins Process for the production of cephalosporins

1994-10-20

1997-01-28

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540215, C07D50118

Patent

active

055979149

ABSTRACT:
A process for etherifying the hydroxymethyl group in position 3 of a cephalosporin by reaction of a 3-hydroxymethyl cephalosporin with an dioxycarbenium-tetrafluoroborate.

REFERENCES:
patent: 5221739 (1993-06-01), Wildfeuer
patent: 5451675 (1995-09-01), Hiragama et al.
The Journal of Antibiotics; Apr., 1992, vol. 45, No. 4 pp. 535-537.
The Journal of Organic Chemistry Mar., 1969, vol. 34, No.3--pp. 627-629.
J. Org. Chem., vol. 42, No. 10, 1977, 1801-1802.
Chem. Abstract 269883r, vol. 120, p. 1015, 1994.
Monatsheffe fur Chemie 117, 375-383 (1986).
Synlett, 1991, No. 10, Oct. , pp. 727-728.

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