Process for the production of 16-Dehydropregenolone acetate form

Organic compounds -- part of the class 532-570 series – Organic compounds – Cyclopentanohydrophenanthrene ring system containing

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07J 700

Patent

active

058081178

ABSTRACT:
The invention relates to a process for producing 16-Dehydropregnenolone acetate (16DPA) of the formula shown below ##STR1## which process comprises a) acetolysis of diosgenin of the formula shown below ##STR2## by heating in a pressure reactor in the presence of an acetylating agent and a non-polar solvent, maintaining the pressure in the reactor in the range of 4-6 kg/cm.sup.2 and at a temperature in the range of 200.degree.-250.degree. C. to produce pseudodiosgenine acetate of the formula shown below ##STR3## b) Oxidizing the so obtained pseudodiosgenin acetate to obtain diosone of the formula shown below ##STR4## and, c) Hydrolysis and degradation of the diosone so obtained to produce the said 16-Dehydropregnenolone acetate.

REFERENCES:
patent: 3136758 (1964-06-01), Chemerda et al.
patent: 4482706 (1984-11-01), Tomimatsu et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Process for the production of 16-Dehydropregenolone acetate form does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the production of 16-Dehydropregenolone acetate form, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of 16-Dehydropregenolone acetate form will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-89716

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.