Process for the preparation of quinolizinone derivatives

Details Process for the preparation of quinolizinone derivatives Process for the preparation of quinolizinone derivatives

1975-05-02

1976-09-28

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260283R, 260289D, 260289C, 424258, C07D48704

Patent

active

039831221

ABSTRACT:
Novel process for the preparation of compounds of the following general structure which are useful as antidepressant and antiparkinson agents: ##SPC1##
Wherein R represents hydrogen, hydroxy, halogen, trifluoromethyl, straight or branched lower alkyl of from 1 to 6 carbon atoms or straight or branched lower alkoxy of from 1 to 6 carbon atoms; R.sub.1 represents hydrogen, lower alkyl of from 1 to 6 carbon atoms, phenyl or benzyl; n is an integer of from 1 to 3; m is an integer of 1 or 2; and individual optical and geometric isomers and pharmaceutically acceptable acid addition salts thereof.

REFERENCES:
von Strandtmann et al., J. Org. Chem., vol. 31, pp. 797-803, (1966).

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