Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1998-06-10
1999-07-20
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
540465, 424 9363, C07F 96524, C07D29518
Patent
active
059257520
ABSTRACT:
A process for the preparation of complexes of macrocyclic chelants with paramagnetic metal trivalent ions of formula (XII) ##STR1## wherein R.sub.1, R.sub.2 and Me.sup.3+ are as described in the following, comprising: a) reaction of 1,4,7,10-tetraazacyclododecane with triethyl orthoformate to give carboxymethylation reaction in water; c) hydrolysis reaction in basic conditions; d) alkylation according to known methods with an epoxide in water; e) complexation according to known methods carried out in water by addition of a paramagnetic metal salt; f) purification by diafiltration, final desalting of the aqueous solution on ion exchange resins and g) crystallization or recovery.
REFERENCES:
patent: 4085106 (1978-04-01), Atkins
patent: 5277895 (1994-01-01), Platzek et al.
patent: 5447635 (1995-09-01), Viscardi et al.
patent: 5747000 (1998-05-01), Platzek et al.
Dischino et al., Inorg. Chem. 1991, 30, pp. 1265-1269.
Weisman et al., Tetrahedram Letters., vol. 21, 1980 pp. 3635-3638.
Ausonio Marina
Cossutta Patrizia
Murru Marcella
Ripa Giorgio
Scala Alessandro
Dibra S.p.A.
Raymond Richard L.
Sripada Pavanaram K
LandOfFree
Process for the preparation of macrocyclic chelants and the chel does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the preparation of macrocyclic chelants and the chel, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of macrocyclic chelants and the chel will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1322884