Process for the preparation of hypoallergenic mosaic antigens

Details Process for the preparation of hypoallergenic mosaic antigens Process for the preparation of hypoallergenic mosaic antigens

2003-12-18

2009-02-17

Haddad, Maher M (Department: 1644)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S275100, C514S002600, C530S350000, C530S370000

Reexamination Certificate

active

07491396

ABSTRACT:
A process for the preparation of an hypoallergenic mosaic antigen derived from an allergen is disclosed whereby a) in a first step the allergen is split into at least two parts and the IgE reactivity of each part is determined and b) in a second step those parts of the allergen which have no detectable IgE reaction are combined to a mosaic antigen which comprises the amino acids of the allergen but the order of the amino acids of the mosaic antigen is different from that of the naturally occurring allergen.

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