Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-12-22
2010-06-08
Saeed, Kamal A (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07732621
ABSTRACT:
The present invention relates to a process for the preparation of an enantiomerically enriched optionally substituted indoline-2-carboxylic acid or a salt thereof, wherein an enantiomerically enriched chiral ortho-X-substituted phenylalanine compound, wherein X is a leaving group, is subjected to cyclisation, preferably at a temperature of below about 140° C., upon formation of the enantiomerically enriched indoline-2-carboxylic acid compound.
REFERENCES:
patent: 2004-182670 (2004-07-01), None
Wagaw, et al, “Palladium-Catalyzed Coupling of Optically Active Amines with Aryl Bromides,” J. Am. Chem. Soc., vol. 119, No. 36, pp. 8451-8458, 1997.
International Search Report dated Apr. 21, 2006.
De Lange Ben
De Vries Andreas Hendrikus Maria
De Vries Johannes Gerardus
Hyett David John
Maas Peter Johannes Dominicus
DSM IP Assets B.V.
Nixon & Vanderhye P.C.
Saeed Kamal A
Shterengarts Samantha L
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