Process for the preparation of an indole derivative

Details Process for the preparation of an indole derivative Process for the preparation of an indole derivative

2005-09-20

2005-09-20

Rotman, Alan L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

06946565

ABSTRACT:
A process for the preparation of methyl 2-(3-chloropropoxy)-indole-3-carboxylate, which comprises reacting a 3-chloro-3-carboxylate indole compound with 3-chloropropanol in the presence of an acid having a pKa of from 0 to 2.

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L. Gaster,Drugs of the Future, 1997, 22(12), pp. 1325-1332.
K.A. Wardle, et al., Br. J. Pharmacol., 1996, 118, pp665-670.

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