Process for the preparation of a particulate antimicrobial produ

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435190, 435192, 435264, 424450, 424 941, 424 944, 514 54, 25217412, 252DIG12, C12P 1904, A61K 3722, A61K 3750

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active

052061566

ABSTRACT:
The invention relates to a process for the preparation of a particulate antimicrobial product from the LP system of the lactoperoxidase enzyme/oxygen donor/oxidizable substrate (if needed). The process comprises bonding the lactoperoxidase enzyme to a particulate carrier comprising a polysaccharide nucleus, a first lipidic layer and a second phospholipidic layer in such a manner that the enzyme molecules are inserted into this second layer and/or into the first layer. The product according to the invention is obtained by then conditioning in a non-aqueous medium the aforesaid particulate vector and the molecules of the LP system not integrated into said vector. The process of the invention permits adjusting the diffusability of the product and its mobility as a function of the intended applications, without destruction of the LP system.

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Chemical Abstracts, vol. 85, No. 25, Abstract No. 190934h.
Hatsuda, Kazuyoshi, Chemical Abstracts, vol. 114, #59713k; p. 471.

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