Process for the preparation of 1,5-didesoxy-1,5-imino-D-glucitol

Details Process for the preparation of 1,5-didesoxy-1,5-imino-D-glucitol Process for the preparation of 1,5-didesoxy-1,5-imino-D-glucitol

1985-05-14

1986-09-09

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

536 41, 536 187, C07D21146

Patent

active

046110585

ABSTRACT:
The invention relates to a process for preparing 1,5-didesoxy-1,5-imino-D-glucitol (desoxynojirimicin) and N-derivative thereof, which are known to be powerful inhibitors for .alpha.-glycosidases. The process of the invention involves reducing with a complex borohydride, a 6-amino-6-desoxy-L-sorbose.

REFERENCES:
patent: 2898379 (1959-08-01), Chamberlain et al.
patent: 4220782 (1980-09-01), Stoltefuss
Chemical Abstracts, 93: 47104x (1980) [Ger. Offen. 2,830,469, Stoltefuss, 1/24/80].

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