Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2007-03-20
2007-03-20
Badio, Barbara P. (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C552S648000
Reexamination Certificate
active
10417559
ABSTRACT:
The process for making crystals of a 11 β-benzaldoxim-estra-4,9-diene derivative having an average particle size of from 3 μm to 25 μm and a maximum particle size of 100 μm, includes subjecting a supersaturated solution containing a special 11β-benzaldoxim-estra-4,9-diene derivative of formula (I) to a wet milling by a wet milling apparatus while crystallizing, In order to obtain a primary particle suspension. Crystals obtained according to this process and pharmaceutical preparations containing them are also described and are part of the invention.
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Norbert Rasenack et al: “Micronization of Anti . . . ” Journal of Pharmaceutical Science, vol. 92, No. 1, Jan. 2003, pp. 35-44.
Eichardt Annette
Gerecke Hagen
Gliesing Sabine
Grawe Detlef
Hoesel Peter
Badio Barbara P.
Schering AG
Striker Michael J.
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