Process for producing cephalosporin analogs

Details Process for producing cephalosporin analogs Process for producing cephalosporin analogs

1980-04-14

1982-06-01

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

546112, C12P 1718

Patent

active

043328962

ABSTRACT:
Optically active cephalosporin analogs are produced by an optically selective acylation reaction. The reaction is carried out in the presence of a microbial enzyme which catalyzes the selective optical acylation. The products thus obtained are useful as antibacterial agents.

REFERENCES:
patent: 3816253 (1974-06-01), Takahashi et al.
patent: 3945888 (1976-03-01), Takohashi et al.
J. Am. Chem. Soc. vol. 96, pp. 7584+7585 (1974).

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