Process for producing a low-molecular weight peptide composition

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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426 7, 426 32, 426 42, 426 44, 426 46, 426 52, 426 56, 426656, 260112R, C12P 2106, A23J 100, A23L 120, A23L 131

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044528884

ABSTRACT:
A low-molecular weight peptide composition mainly based on dipeptides and tripeptides is produced by dispersing protein raw material from any suitable source in water at a concentration of 5 to 20 w/v %, adjusting the pH of the dispersion to 1 to 4 with an acid, adding at least two acid proteases to the dispersion, and permitting enzymatic proteolysis to take place for a desired period of time at a suitable temperature while supressing the formation of free amino acids. Also provided is a nutrient agent comprising the thus produced low-molecular weight peptide composition mainly based on dipeptides and tripeptides wherein the contents of free amino acids and those peptides having a molecular weight of at least 700 are individually 20% by weight or less. The nutrient agent is useful in medical treatment.

REFERENCES:
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patent: 2473255 (1949-06-01), Parfentjev
patent: 4138500 (1979-02-01), Fulger et al.
patent: 4282319 (1981-08-01), Conrad
T. Nakadai et al., J. Ferment. Technol., vol. 54, No. 12, (1976), pp. 872-884.
Proc. IV Int. Cong. Food Sci. & Technol. (1974), vol. V, pp. 96-102.
Br. J. Nutrition, vol. 33, No. 1, (Jan. 1975), pp. 95-100.

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