Process for producing 5-methyluridine and purification by sedime

Details Process for producing 5-methyluridine and purification by sedime Process for producing 5-methyluridine and purification by sedime

1995-04-17

1996-08-20

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435822, 536 2712, C12P 1938, C07H 1900

Patent

active

055478573

ABSTRACT:
The present provides a process for obtaining high-purity 5-methyluridine crystals from nucleic acid ingredients as starting materials using a microorganism. The process comprises culturing a microorganism, removing part or the whole of the culture medium ingredients, conducting the enzyme reaction by the microorganism, crystallizing 5-methyluridine formed, and separating the obtained crystals from other impurity crystals on the basis of a difference in the precipitation rate.

REFERENCES:
patent: 4381344 (1983-04-01), Rideout et al.
patent: 5258301 (1993-11-01), Yamauchi et al.
patent: 5384251 (1995-01-01), Yamauchi et al.

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