Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1996-11-19
1998-09-15
Clardy, S. Mark
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544353, 546174, 546175, 546176, 546177, 546273, 548159, 548548, 548181, 548217, 514249, 514259, 514314, 514339, 514365, 514367, 514374, C07D24100, C07D40110, C07D40112, A61K 3147
Patent
active
058078665
ABSTRACT:
A process for producing a compound of the formu5la ##STR1## comprising the step of reacting a compound of the formula ##STR2## with a compound of the formula ##STR3## to form a compound of the formula ##STR4## wherein R.sup.2a is selected from the groups recited above for R.sup.2, or R.sup.2a --X-- is a protected hydroxyl group, and Z is a group of formula --Y--R.sub.5 recited above, or a group that can be converted into a group of said formula --Y--R.sup.5. Intermediates of formula IV and composition containing substantially optically pure enantiomers of Formula (I) are included within the scope of the invention.
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Bach Nicholas James
Baker Stephen Richard
Gilmore Jeremy
Lewthwaite Russell Andrew
McKillop Alexander
Barrett Brian P.
Boone David E.
Clardy S. Mark
Eli Lilly and Company
Qazi Sabiha N.
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