Process for preparing lipophilic oligosaccharide antibiotics

Details Process for preparing lipophilic oligosaccharide antibiotics Process for preparing lipophilic oligosaccharide antibiotics

1998-11-30

2000-12-19

Fonda, Kathleen K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 185, 536 187, 536 551, 536 553, 514 54, C07H 100, A61K 31715

Patent

active

061629103

ABSTRACT:
Process for preparing a lipophilic oligosaccharide antibiotic containing a nitro group using oxidizing agents and catalysts such as cobalt, manganese and copper having an oxidation state of +2 are disclosed.

REFERENCES:
patent: 4375361 (1983-03-01), Lyons et al.
patent: 5624914 (1997-04-01), Patel et al.
patent: 5776912 (1998-07-01), Patel et al.
A.K. Ganguly et al., Chemical Modification of Everninomicins, The Journal of Antibiotics, vol XXXV No. 5, (May 1982), pp. 561-570.
S. Kalliney et al., An Efficient Peroxidase-Catalyzed Oxidation of Hydroxylaminoeverninomicin in Aqueous-Organic Media, Tetrahedron Letters, vol. 36, No. 24, (1995), pp. 4163-4166.

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