Process for preparing 4-amino-5-dialkoxy-methylpyrimidine deriva

Details Process for preparing 4-amino-5-dialkoxy-methylpyrimidine deriva Process for preparing 4-amino-5-dialkoxy-methylpyrimidine deriva

1983-01-26

1985-01-08

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23902

Patent

active

044927924

ABSTRACT:
A process for preparing a 4-amino-5-dialkoxymethylpyrimidine derivative of the formula: ##STR1## which comprises reacting a propanenitrile derivative represented by the formula (I) or the novel compound represented by formula (II): ##STR2## with an amidine of the formula: ##STR3## wherein R.sup.1 to R.sup.6 are as defined in the specification. Also disclosed is a process for making the novel compounds of formula (II).

REFERENCES:
patent: 2602794 (1952-07-01), Hitchings
patent: 3036075 (1962-05-01), Kaiser
patent: 3956327 (1976-05-01), Cresswell
patent: 4039543 (1977-08-01), Kompis
Bredereck, Chem. Ber. 106, 3743 (1973).

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