Process for preparing 1-alkylimidazoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D23358

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active

050119346

ABSTRACT:
Imidazoles are alkylated at the 1-position by adding an alkyl halide a mixture comprising an imidazole, a non-reactive aromatic solvent and a base at temperature of from about 75.degree. C. to about 115.degree. C. and then maintaining the temperature for a period of time sufficient to produce the 1-alkylimidazole and then separating any inorganic material from the product.

REFERENCES:
patent: 4062965 (1977-12-01), Holtschmidt et al.
patent: 4301170 (1981-11-01), Houlihan

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