Process for preparation of phenethylamine derivatives

Details Process for preparation of phenethylamine derivatives Process for preparation of phenethylamine derivatives

2007-02-20

2007-02-20

Davis, Brian (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

Reexamination Certificate

active

10797705

ABSTRACT:
A process for the preparation of a compound of formula I,wherein R1and R2are ortho or para substituents, independently selected from the group consisting of hydrogen, hydroxyl, C1–C6alkyl, C1–C6alkoxy, C7–C9aralkoxy, C2–C7alkanoyloxy, C1–C6alkylmercapto, halo and trifuoromethyl; R3is hydrogen or C1–C6alkyl 1, 2, 3 or 4; and the dotted line represents optional olefinic unsaturation;comprising hydrogenating a compound of formula III,in the presence of a nickel or cobalt catalyst at a temperature of about 5° C. to 25° C.

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