Process for penem derivatives

Details Process for penem derivatives Process for penem derivatives

1986-06-02

1988-11-01

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540310, C07D49904, A61K 31425

Patent

active

047821450

ABSTRACT:
An efficient process for converting readily available 4-acetoxy-2-azetidinones to allyl 2-thioxopenam-3-carboxylates, intermediates useful for the synthesis of penem antibiotics.

REFERENCES:
patent: 4530793 (1985-07-01), Girijavallabhan
patent: 4585874 (1986-04-01), Alpegiani et al.
patent: 4675396 (1987-06-01), Ross et al.
patent: 4695626 (1987-09-01), Brighty
Leanza et al., Tetrahedron, 39, pp. 2505-2513 (1983).
Ganguly et al., Journal of Antimicrobial Chemotherapy, 9, Suppl. C, pp. 1-6 (1982).

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