Process for the synthesis of penems

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D49900, A61K 31425

Patent

active

047821469

ABSTRACT:
A process for the synthesis of penems from azetidinones via 1-aza-4,5-dithiabicyclo[4.2.0]oct-2-en-8-one-2-carboxylate esters.

REFERENCES:
patent: 3835130 (1974-09-01), Woodward
patent: 4585874 (1986-04-01), Alpegiani et al.
Leanza et al., Tetrahedron 39, pp. 2505-2513 (1983).
Ganguly et al., Journal of Antimicrobial Chemotherapy 9, Suppl. C, pp. 1-6 (1982).

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