Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1978-11-16
1982-06-15
Trousof, Natalie
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
260465D, C07C10112
Patent
active
043352561
ABSTRACT:
A two-step process for manufacturing d,l-.beta.-benzoylamino-isobutyric acid is disclosed, wherein in the first step benzamide is reacted with methacrylonitrile in the presence of an alkaline catalyst in an anhydrous solvent medium at atmospheric pressure, thus obtaining d,l-.beta.-benzoylamino-isobutyronitrile, which, in the second process step, without necessarily being previously crystallized is directly hydrolyzed to d,l-.beta.-benzoylamino-isobutyric acid.
REFERENCES:
patent: 2461842 (1949-02-01), Olin
patent: 2510784 (1950-06-01), Lucas
patent: 2849477 (1958-08-01), Dornow et al.
patent: 3489793 (1970-01-01), Bertelli
De Witt Paolo
Diamanti Enrico
Adams Bruce L.
Burns Robert E.
Clarke Vera C.
Lobato Emmanuel J.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
LandOfFree
Process for manufacturing d,l-.beta.-benzoylamino-isobutyric aci does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for manufacturing d,l-.beta.-benzoylamino-isobutyric aci, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for manufacturing d,l-.beta.-benzoylamino-isobutyric aci will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1920050